Beth Bioinformatiics Co., Limited

Project Leader: Prof. Maggie Haitian WANG
Key Technology Area: Biotechnology
Industrial Sectors: Pharmaceutical and Healthcare Products
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Description

Beth Bioinformatics (BethBio) is a biotech company that develops state-of-the-art technologies to empower the development of new and better vaccines. Utilizing virology, AI and computational biology, BethBio provides a series of innovating bioinformatics solutions to pharmaceutical companies, including virus evolution prediction, candidate vaccine strain selection, optimized antigen design, vaccine effectiveness (VE) estimation in-silico, clinical trial design, codon optimization / deoptimization and more. 


One of BethBio’s signature technology is accurate prediction of virus evolution, developed using viral genome analysis and bioinformatics modeling and applicable to many viruses including SARS-CoV-2, Influenza and more. With it, BethBio is able to develop better vaccine candidates that are more resilient against future viral mutations and would provide better protection against circulating viruses for their clients.


These solutions could help our clients solve various technical difficulties such as protein expression, increase VE or manufacture efficiency of their vaccines, and improve chances of obtaining regulatory approval. For instance, from study results, BethBio’s solutions are able to improve the VE of seasonal influenza vaccines by around 20%.


BethBio’s technologies are applicable to every vaccine platform, meaning we could serve all kinds of clients. The company is already working closely with pharmaceutical companies, including several new vaccine co-development projects.

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